CUSTOM ITEM: HPLC Column, RP PFP, 3um, 4.0mm ID x 50mm Length, 100A. Cogent Brand. 1 EA.
Additional Info:
The 68322‑05P‑4 Cogent RP PFP™ HPLC Column is designed for enhanced selectivity of halogenated, aromatic, and polar compounds, delivering improved separation performance where traditional C18 phases may not fully resolve analytes.
This stationary phase incorporates a pentafluorophenyl (PFP, “F5”) ligand bonded via a four‑carbon linker to high‑purity silica with full double end‑capping, enabling multiple interaction mechanisms including π‑π interactions, dipole interactions, and hydrogen bonding. These interactions provide greater selectivity control and improved resolution of structurally similar compounds.
The 100 Å pore size offers versatility for a wide range of analytes, making this column well suited for both routine analytical and method development applications.
50 mm Length – Fast Analytical Screening
The 50 mm length is optimized for rapid separations and method development, allowing quick evaluation of selectivity.
Short run times for high throughput
Efficient screening of retention and selectivity
Reduced solvent consumption
✅ Use when speed and fast decision‑making are priorities in analytical workflows
Flow Rate & System Requirements (4.0 mm ID, 3 µm)
⚠️ Compatible with standard HPLC systems, with moderate backpressure
Typical flow rate range: ~0.8–1.5 mL/min
Balanced efficiency and pressure vs 5 µm columns
Suitable for analytical detectors
Monitor pressure due to 3 µm particle size
✅ Sample preparation requirement: filter samples using a 0.2 µm syringe filter prior to injection
Why Choose PFP (F5) for Selective Separations
Enhanced Retention for Halogenated Compounds
Strong interaction with fluorinated and halogenated analytes
Improved selectivity vs C18
Multiple Interaction Mechanisms
π‑π interactions for aromatic compounds
Dipole and hydrogen bonding interactions
Greater flexibility in method development
Balanced Selectivity (100 Å Pore)
Suitable for a wide range of compounds
Effective for both small and moderately sized molecules
Cogent RP PFP™ Advantages
Fully End‑Capped Surface
Minimizes silanol activity
Improves peak symmetry
High Efficiency (3 µm Particles)
Higher efficiency than 5 µm columns
Sharper peaks and improved resolution
High Purity Silica
Consistent chromatographic performance
Reliable reproducibility across runs
Typical Applications
Halogenated compound analysis
Aromatic compound separations
Pharmaceutical analytical workflows
Method development and screening
USP L43 method applications
Important Usage Notes
Packed and shipped in reversed‑phase solvents
Designed for standard analytical HPLC systems (4.0 mm ID)
Higher backpressure than larger particle sizes
👉 Made‑to‑Order Columns & Pricing Information
This is a custom, made‑to‑order column.
Columns are manufactured specifically to order
Orders cannot be canceled once placed
Custom columns are non‑returnable